Propylthiouracil-related Toxic Hepatitis: Impact of Silent Cases
نویسندگان
چکیده
منابع مشابه
Propylthiouracil-related Toxic Hepatitis: Impact of Silent Cases
Liver is the main organ which can metabolize many drugs or chemical agents. Toxic events developed by drugs are one of the most common causes of liver damage. Toxic hepatitis can be encountered in different clinical situations, such as acute hepatitis, fulminant hepatitis chronic hepatitis or cirrhosis. We aimed to report a case of asymptomatic toxic hepatitis in a patient taking propylthiourac...
متن کاملRelationship of recovered hepatitis B infection with appearance of toxic propylthiouracil hepatitis.
Aim To investigate the relationship between recovered hepatitis B infection with appearance of toxic propylthiouracil (PTU) hepatitis and point out the growing importance of the use of drugs in the development of hepatitis. Methods A case of a 45-year-old female patient with suspicion of acute viral hepatitis who had polypragmasy of drugs in the last ten years, due to the polymorphism of sympto...
متن کاملComparison of Two Propylthiouracil Preparations in Treatment of Toxic Goiter
In order to compare the effect of propylthiouracil (PTU) of Iran Hormone Co. and that of Dr. Herbrand KG, Germany, 28 patients with toxic goiter entered this study. Each patient received 200 mg PTU daily for the first 4 weeks and 50 mg daily thereafter. 17 patients received PTU from Iran Hormone (group 1) and 111 took PTU from Germany (group 2). T4, T3 and TSH by RIA and resine T3, uptake were ...
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We present a case of a 27-year-old para 2þ 0 who had a normal delivery 2 years previously. She had a previous cone biopsy for CIN3 and was receiving annual smears. She was referred by her GP to our A&E department with a 24 h history of generally feeling unwell, with diarrhoea, vomiting and lower abdominal pain. Her temperature was 388C; she was hypotensive (blood pressure 72/ 38 mmHg), with a r...
متن کاملPropylthiouracil, and methimazole, and carbimazole-related hepatotoxicity.
INTRODUCTION Propylthiouracil (PTU) has been used for the treatment of hyperthyroidism since the 1940s, but over the years reports of significant hepatotoxicity have come forth, particularly in children. This led to a black box warning being issued by the US FDA in 2009, followed by a similar warning by the European Medicines Agency and the United Kingdom Medicines and Healthcare Regulatory Age...
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ژورنال
عنوان ژورنال: Euroasian Journal of Hepato-Gastroenterology
سال: 2015
ISSN: 2231-5047,2231-5128
DOI: 10.5005/jp-journals-10018-1153